Invite Only And Off The Record Event
No single group has more influence over the U.S. healthcare system than enterprise benefits leaders. A private, two-day gathering of senior benefits leaders, physicians, and scientists working through the biology, the AI, and the everyday experience that are changing healthcare.
Napa Valley · April 14th–15th
The Experience
The two days in Napa don't start when you land — they start weeks before, with your own biology. Here's how it unfolds, from the test at your kitchen table to the last glass at Hall Winery.
3 months out
An at-home genetic, gut microbiome, and blood test arrives at your door — a few minutes, done from home.
1 month out
A virtual webinar to get to know the room before you're in it — the faces, the themes, the argument.
Apr 14 · Midday
Check in at Silverado Resort — the golf course and the spa are yours to use around the program.
Apr 14 · Afternoon
Receive your testing results, private to you and yours to keep — and meals personalized to your biology from here on.
Apr 14–15
Work through the argument with industry peers — on panels, over long breaks, and at hosted dinners.
Apr 14 & 15
Opening and closing keynotes from physicians and scientists educating the room on the now—and the frontier—of care and healthspan.
Apr 15
The room closes with a private hosting and tasting at Hall Winery — +1s welcome.
The Room
Half-Life:100 isn't a conference, and there's no audience to sit in one. Every person in the room is faculty. You'll choose your part before you arrive — a panel seat, a lightning talk, or leading a table — and you'll spend a day and a half in candid company with roughly forty peers who are just as tired of twelve disconnected breakout sessions as you are. No booths. No sponsor stage. No badge that says press.
What's said in Napa is said off the record, by design. That's the whole invitation.
Who's At The Table
We build this room deliberately. Senior benefits leaders — from midsize employers to Fortune 1 — set the agenda; physicians, scientists, and AI experts sharpen it. The balance keeps the conversation where it belongs: on the evidence and the economics.
The Room
Leaders who carry benefits decisions for tens of thousands of lives, and who don't have time for guesswork. Every seat is intentional. Every topic lands where the pressure sits: cost, transformation, and an innovation worth betting on.
Benefits leaders
The core of the room, and the reason it exists.
Physicians and scientists
AI Experts
The Curriculum
Every session in Napa is examined through one of three lenses. Rather than treating them as isolated trends, they form the foundation of a single, continuous argument the room will spend two days building together.
Biology
Artificial Intelligence
Human Experience
The Arc
One argument, carried across a day and a half — not twelve disconnected breakouts stitched into an agenda. Roughly a quarter of the clock is left unprogrammed, on purpose: the sessions make the case, the long breaks are where it actually lands.
Act I · Predict
Wed, Apr 14
What biology already knows about a claim before it happens.
Acts II–III · Personalize / Participate
Thu, Apr 15
From biology-matched care to a framework you can use Monday.
If you'd like to be considered for the room, tell us a bit about yourself and how you'd like to contribute: a panel seat, a lightning talk or leading a table.
What Is Half-Life:100
The chronic conditions driving healthcare costs are not inevitabilities of age. They are biological diseases — and biological diseases can be intercepted. Medicine has become very good at adding years to life and strikingly bad at adding health to those years: in the U.S., the gap between lifespan and healthspan now runs 12.4 years.
This initiative exists to put the genuine frontier of precision biology and AI-orchestrated care into the hands of the enterprise benefits leaders who can deploy it at a population scale. It is our way of giving back to the community of benefits leaders, and to society — driving a more cost-effective, healthier future for the country.